Cisplatin

The Penicillin of Cancer

Cisplatin Research


Chronopharmacology of cisplatin: Role of the circadian rhythm in modulating the cisplatin transporters levels

Cisplatin induces mitochondrial damage and hippocampal neurotoxicity: a potential mechanism for chemotherapy-related cognitive impairment

Loss of MGMT promoter methylation and resistance to cisplatin in non-seminomatous germ cell tumors

Single cell cisplatin measurements by ICP-MS

Chloroquine-induced lysosomal membrane permeabilization restores sensitivity to cisplatin in refractory lung cancer cells

Dichloroacetate Prevents Cisplatin-Induced Nephrotoxicity without Compromising Cisplatin Anticancer Properties

Dichloroacetate Prevents Cisplatin-Induced Nephrotoxicity without Compromising Cisplatin Anticancer Properties

Pharmacological focal adhesion kinase (FAK) inhibition suppresses cisplatin-resistant human ovarian carcinoma growth.

A comparison of the mechanisms and cytotoxic activity of dianhydrogalactitol (VAL-083) to cisplatin in ovarian tumor models harboring wild-type and mutant p53.

A novel assay to predict cisplatin resistance in cancer cells

Analysis of continuous firstline treatment with docetaxel and carboplatin for advanced nonsmall cell lung cancer

A phase II trial of decitabine in combination with carboplatin vs carboplatin alone in patients with ovarian cancer

Risk Stratification Protocol For Carboplatin and Oxaliplatin Hypersensitivity Reactions With Repeat Skin Testing Improves Care

Chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer

Economic impact of a genetic test for cisplatin-induced ototoxicity - Nature

Magnetic medicines hit the cancerous spot

New platinum drug candidate shows promise against cancer

Analysis of single, cisplatin-induced DNA bends by atomic force microscopy and simulations

MIT cancer biologists have shown how resistance to cisplatin arises

Proteasome inhibitors prevent cisplatin-induced mitochondrial release of apoptosis-inducing factor and markedly ameliorate cisplatin nephrotoxicity.

Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

A Comparative Study on Weekly Versus Three Weekly Cisplatinum Based Chemoradiation in Locally Advanced Head and Neck Cancers