? Classes of alkylating agents

Nitrogen mustard analogues

Nitrogen mustard analogues

Generic name Brand name Use in cancer Route
Mechlorethamine Mustargen Hodgkin disease, lymphosarcoma, certain leukemias, mycosis fungoides, and other cancers IV
Cyclophosphamide Cytoxan, Neosar Lymphoma, leukemias, multiple myeloma, mycosis fungoides, neuroblastoma, retinoblastoma, and cancers of the breast and ovary Oral (tablet, liquid), IV
Chlorambucil Leukeran CLL, Hodgkin and non-Hodgkin lymphoma, others Oral
Melphalan   Multiple myeloma, as well as ovarian, breast, and prostate cancer Oral, IV
Ifosfamide Ifex Lymphoma, leukemia, testicular, and bladder cancers. IV
Trofosfamide Ixoten Cyclophosphamide prodrug  
Estramustine Emcyt Advanced prostate cancer, conjugated with estradiol Oral


The penicillin of cancer.
cisplatin molecule
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