Nitrogen mustard analogues
| Generic name | Brand name | Use in cancer | Route |
| Mechlorethamine | Mustargen | Hodgkin disease, lymphosarcoma, certain leukemias, mycosis fungoides, and other cancers | IV |
| Cyclophosphamide | Cytoxan, Neosar | Lymphoma, leukemias, multiple myeloma, mycosis fungoides, neuroblastoma, retinoblastoma, and cancers of the breast and ovary | Oral (tablet, liquid), IV |
| Chlorambucil | Leukeran | CLL, Hodgkin and non-Hodgkin lymphoma, others | Oral |
| Melphalan | Multiple myeloma, as well as ovarian, breast, and prostate cancer | Oral, IV | |
| Ifosfamide | Ifex | Lymphoma, leukemia, testicular, and bladder cancers. | IV |
| Trofosfamide | Ixoten | Cyclophosphamide prodrug | |
| Estramustine | Emcyt | Advanced prostate cancer, conjugated with estradiol | Oral |
Alkyl sulfonates
| Generic name | Brand name | Use | Route |
| Busulfan | Myleran | CML, other blood cancers | Oral |
| Treosulfan | Ovastat (foreign) | Busulfan analogue | |
| Mannosulfan | Busulfan analogue |